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Lipirex

Lipirex

160 mg

Active Ingredient: Fenofibrate

Lipirex

Fenofibrate

Generic Lipirex

Cholesterol Lowering

Class of medication

Fibric acid derivatives

Common Side Effects

Back pain / Chronic indigestion / Troubled breathing / Increased sensitivity of the skin to sunlight /

Used for

Hyperlipoproteinemia

Information about

  • In rare cases, fenofibrate can cause a condition that results in the breakdown of skeletal muscle tissue, leading to kidney failure.
  • Fenofibrate clearance is also reduced in patients with mild to moderate renal impairment.

Dosage

  • Large overdoses may result in reversible cardiac conduction defects or dysrhythmias, apnea, coma and seizures.
  • The common dose for children is between 200 and 400 mg twice a day for up to 10 days.
  • If you notice any unusual changes, call your doctor right away.
  • In the event of an overdose, institute general supportive measures.

Warning

  • Once you stop taking this drug, it may cause your blood sugar levels to increase.
  • Stopping suddenly can cause serious side effects.
  • However, patients with known CV disease or risk factors had a higher absolute incidence of excess serious CV thrombotic events, due to their increased baseline rate.
  • The manufacturers, Eli Lilly, warn that it can lead to liver damage, abnormal bleeding, and skin reactions.
  • Tell your doctor if you drink, or have ever drunk large amounts of alcohol.
  • Thrombosis has occurred in patients taking fenofibrate.
  • Periodic determination of serum lipids should be obtained during initial therapy in order to establish the lowest effective dose of fenofibrate.
  • Fenofibrate and simvastatin should administered concomitantly only with caution.
  • Instruct patient not to consume chipped or broken tablets.
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If coadministered with a strong CYP2C8 inhibitor like gemfibrozil, the maximum recommended dose of pioglitazone is 15 mg daily. Many people using this medication do not have serious side effects. Fenofibrate and rosiglitazone lower serum triglycerides with opposing effects on body weight.

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